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Translesion Synthesis: Insights into the Selection and Switching of DNA Polymerases
DNA replication is constantly challenged by DNA lesions, noncanonical DNA structures and difficult-to-replicate DNA sequences. Two major strategies to rescue a stalled replication fork and to ensure continuous DNA synthesis are: (1) template switching and recombination-dependent DNA synthesis; and (...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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MDPI
2017
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5295019/ https://www.ncbi.nlm.nih.gov/pubmed/28075396 http://dx.doi.org/10.3390/genes8010024 |