Applying Human ADAR1p110 and ADAR1p150 for Site-Directed RNA Editing—G/C Substitution Stabilizes GuideRNAs against Editing

Site-directed RNA editing is an approach to reprogram genetic information at the RNA level. We recently introduced a novel guideRNA that allows for the recruitment of human ADAR2 to manipulate genetic information. Here, we show that the current guideRNA design is already able to recruit another huma...

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Detalles Bibliográficos
Autores principales: Heep, Madeleine, Mach, Pia, Reautschnig, Philipp, Wettengel, Jacqueline, Stafforst, Thorsten
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5295028/
https://www.ncbi.nlm.nih.gov/pubmed/28098820
http://dx.doi.org/10.3390/genes8010034

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5295028/
https://www.ncbi.nlm.nih.gov/pubmed/28098820
http://dx.doi.org/10.3390/genes8010034

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