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SHP2, SOCS3 and PIAS3 Expression Patterns in Medulloblastomas: Relevance to STAT3 Activation and Resveratrol-Suppressed STAT3 Signaling

Background: Activated STAT3 signaling is critical for human medulloblastoma cells. SHP2, SOCS3 and PIAS3 are known as the negative regulators of STAT3 signaling, while their relevance to frequent STAT3 activation in medulloblastomas remains unknown. Methods: Tissue microarrays were constructed with...

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Detalles Bibliográficos
Autores principales: Li, Cong, Li, Hong, Zhang, Peng, Yu, Li-Jun, Huang, Tian-Miao, Song, Xue, Kong, Qing-You, Dong, Jian-Li, Li, Pei-Nan, Liu, Jia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5295047/
https://www.ncbi.nlm.nih.gov/pubmed/28035977
http://dx.doi.org/10.3390/nu9010003