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Regulation of hepatic microRNA expression by hepatocyte nuclear factor 4 alpha

AIM: To uncover the role of hepatocyte nuclear factor 4 alpha (HNF4α) in regulating hepatic expression of microRNAs. METHODS: Microarray and real-time PCR were used to determine hepatic expression of microRNAs in young-adult mice lacking Hnf4α expression in liver (Hnf4α-LivKO). Integrative genomics...

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Detalles Bibliográficos
Autores principales: Lu, Hong, Lei, Xiaohong, Liu, Jerry, Klaassen, Curtis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Baishideng Publishing Group Inc 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5295159/
https://www.ncbi.nlm.nih.gov/pubmed/28217257
http://dx.doi.org/10.4254/wjh.v9.i4.191