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Impact of high dose vitamin C on platelet function

AIM: To examine the effect of high doses of vitamin C (VitC) on ex vivo human platelets (PLTs). METHODS: Platelet concentrates collected for therapeutic or prophylactic transfusions were exposed to: (1) normal saline (control); (2) 0.3 mmol/L VitC (Lo VitC); or (3) 3 mmol/L VitC (Hi VitC, final conc...

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Detalles Bibliográficos
Autores principales: Mohammed, Bassem M, Sanford, Kimberly W, Fisher, Bernard J, Martin, Erika J, Contaifer Jr, Daniel, Warncke, Urszula Osinska, Wijesinghe, Dayanjan S, Chalfant, Charles E, Brophy, Donald F, Fowler III, Alpha A, Natarajan, Ramesh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Baishideng Publishing Group Inc 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5295168/
https://www.ncbi.nlm.nih.gov/pubmed/28224106
http://dx.doi.org/10.5492/wjccm.v6.i1.37