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Global DNA methylation levels are altered by modifiable clinical manipulations in assisted reproductive technologies
BACKGROUND: We analyzed placental DNA methylation levels at repeated sequences (LINE1 elements) and all CCGG sites (the LUMA assay) to study the effect of modifiable clinical or laboratory procedures involved in in vitro fertilization. We included four potential modifiable factors: oxygen tension du...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5295214/ https://www.ncbi.nlm.nih.gov/pubmed/28191261 http://dx.doi.org/10.1186/s13148-017-0318-6 |