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Global DNA methylation levels are altered by modifiable clinical manipulations in assisted reproductive technologies

BACKGROUND: We analyzed placental DNA methylation levels at repeated sequences (LINE1 elements) and all CCGG sites (the LUMA assay) to study the effect of modifiable clinical or laboratory procedures involved in in vitro fertilization. We included four potential modifiable factors: oxygen tension du...

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Detalles Bibliográficos
Autores principales:	Ghosh, Jayashri, Coutifaris, Christos, Sapienza, Carmen, Mainigi, Monica
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2017
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5295214/ https://www.ncbi.nlm.nih.gov/pubmed/28191261 http://dx.doi.org/10.1186/s13148-017-0318-6

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