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The In Vitro and In Vivo Anti-Inflammatory Effects of a Phthalimide PPAR-γ Agonist

Previously, the authors found that 4-hydroxy-2-(4-hydroxyphenethyl) isoindoline-1,3-dione (PD1) (a phthalimide analogue) bound to and activated peroxisome proliferator-activated receptor-γ (PPAR-γ). Since PPAR-γ suppresses inflammatory responses, the present study was undertaken to investigate the a...

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Detalles Bibliográficos
Autores principales: Su, Mingzhi, Cao, Jiafu, Huang, Jin, Liu, Sen, Im, Dong Soon, Yoo, Jin-Wook, Jung, Jee H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5295227/
https://www.ncbi.nlm.nih.gov/pubmed/28054961
http://dx.doi.org/10.3390/md15010007