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Excavatolide B Attenuates Rheumatoid Arthritis through the Inhibition of Osteoclastogenesis
Osteoclasts are multinucleated giant cells of macrophage/monocyte lineage, and cell differentiation with the upregulation of osteoclast-related proteins is believed to play a major role in the destruction of the joints in the course of rheumatoid arthritis (RA). Pro-inflammatory cytokines, such as i...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5295229/ https://www.ncbi.nlm.nih.gov/pubmed/28067799 http://dx.doi.org/10.3390/md15010009 |