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Excavatolide B Attenuates Rheumatoid Arthritis through the Inhibition of Osteoclastogenesis

Osteoclasts are multinucleated giant cells of macrophage/monocyte lineage, and cell differentiation with the upregulation of osteoclast-related proteins is believed to play a major role in the destruction of the joints in the course of rheumatoid arthritis (RA). Pro-inflammatory cytokines, such as i...

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Detalles Bibliográficos
Autores principales: Lin, Yen-You, Jean, Yen-Hsuan, Lee, Hsin-Pai, Lin, Sung-Chun, Pan, Chieh-Yu, Chen, Wu-Fu, Wu, Shu-Fen, Su, Jui-Hsin, Tsui, Kuan-Hao, Sheu, Jyh-Horng, Sung, Ping-Jyun, Wen, Zhi-Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5295229/
https://www.ncbi.nlm.nih.gov/pubmed/28067799
http://dx.doi.org/10.3390/md15010009