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Asymmetric Total Synthesis of Ieodomycin B

Ieodomycin B, which shows in vitro antimicrobial activity, was isolated from a marine Bacillus species. A novel asymmetric total synthetic approach to ieodomycin B using commercially available geraniol was achieved. The approach involves the generation of 1,3-trans-dihydroxyl at C-3 and C-5 position...

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Detalles Bibliográficos
Autores principales: Lin, Shuangjie, Zhang, Jianting, Zhang, Zhibin, Xu, Tianxiang, Huang, Shuangping, Wang, Xiaoji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5295237/
https://www.ncbi.nlm.nih.gov/pubmed/28106760
http://dx.doi.org/10.3390/md15010017