Conditional ablation of HDAC3 in islet beta cells results in glucose intolerance and enhanced susceptibility to STZ-induced diabetes

Histone deacetylases (HDACs) are enzymes that regulate gene expression by modifying chromatin structure through removal of acetyl groups from target histones or non-histone proteins. Previous in vitro studies suggest that HDACs may be novel pharmacological targets in immune-mediated islet β-cell des...

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Detalles Bibliográficos
Autores principales: Chen, Wen-Bin, Gao, Ling, Wang, Jie, Wang, Yan-Gang, Dong, Zheng, Zhao, Jiajun, Mi, Qing-Sheng, Zhou, Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Perspective: Pathology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5295367/
https://www.ncbi.nlm.nih.gov/pubmed/27542279
http://dx.doi.org/10.18632/oncotarget.11295

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5295367/
https://www.ncbi.nlm.nih.gov/pubmed/27542279
http://dx.doi.org/10.18632/oncotarget.11295

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