Kukoamine B promotes TLR4-independent lipopolysaccharide uptake in murine hepatocytes

Free bacterial lipopolysaccharide (LPS) is generally removed from the bloodstream through hepatic uptake via TLR4, the LPS pattern recognition receptor, but mechanisms for internalization and clearance of conjugated LPS are less clear. Kukoamine B (KB) is a novel cationic alkaloid that interferes wi...

Descripción completa

Detalles Bibliográficos
Autores principales: Yang, Dong, Zheng, Xinchuan, Wang, Ning, Fan, Shijun, Yang, Yongjun, Lu, Yongling, Chen, Qian, Liu, Xin, Zheng, Jiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Perspective: Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5295368/
https://www.ncbi.nlm.nih.gov/pubmed/27542278
http://dx.doi.org/10.18632/oncotarget.11292

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5295368/
https://www.ncbi.nlm.nih.gov/pubmed/27542278
http://dx.doi.org/10.18632/oncotarget.11292

Ejemplares similares