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NFIB overexpression cooperates with Rb/p53 deletion to promote small cell lung cancer

Small cell lung cancer (SCLC) is a highly aggressive neuroendocrine tumor type that is typically metastatic upon diagnosis. We have a poor understanding of the factors that control SCLC progression and metastasis. TheNFIB transcription factor is frequently amplified in mouse models of SCLC, but clea...

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Detalles Bibliográficos
Autores principales: Wu, Nan, Jia, Deshui, Ibrahim, Ali H., Bachurski, Cindy J., Gronostajski, Richard M., MacPherson, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5295369/
https://www.ncbi.nlm.nih.gov/pubmed/27613844
http://dx.doi.org/10.18632/oncotarget.11583