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NFIB overexpression cooperates with Rb/p53 deletion to promote small cell lung cancer
Small cell lung cancer (SCLC) is a highly aggressive neuroendocrine tumor type that is typically metastatic upon diagnosis. We have a poor understanding of the factors that control SCLC progression and metastasis. TheNFIB transcription factor is frequently amplified in mouse models of SCLC, but clea...
Autores principales: | Wu, Nan, Jia, Deshui, Ibrahim, Ali H., Bachurski, Cindy J., Gronostajski, Richard M., MacPherson, David |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5295369/ https://www.ncbi.nlm.nih.gov/pubmed/27613844 http://dx.doi.org/10.18632/oncotarget.11583 |
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