Cargando…

Downregulation of the phosphatase JKAP/DUSP22 in T cells as a potential new biomarker of systemic lupus erythematosus nephritis

Systemic lupus erythematosus (SLE) is a complex autoimmune disease that is characterized by systemic inflammation and multiple organ failures. Dysregulation of T cells plays a critical role in SLE pathogenesis. Our previous study indicates that JKAP (also named DUSP22) inhibits T-cell activation and...

Descripción completa

Detalles Bibliográficos
Autores principales: Chuang, Huai-Chia, Chen, Yi-Ming, Hung, Wei-Ting, Li, Ju-Pi, Chen, Der-Yuan, Lan, Joung-Liang, Tan, Tse-Hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5295375/
https://www.ncbi.nlm.nih.gov/pubmed/27557500
http://dx.doi.org/10.18632/oncotarget.11419