Cargando…

Downregulation of the phosphatase JKAP/DUSP22 in T cells as a potential new biomarker of systemic lupus erythematosus nephritis

Systemic lupus erythematosus (SLE) is a complex autoimmune disease that is characterized by systemic inflammation and multiple organ failures. Dysregulation of T cells plays a critical role in SLE pathogenesis. Our previous study indicates that JKAP (also named DUSP22) inhibits T-cell activation and...

Descripción completa

Detalles Bibliográficos
Autores principales:	Chuang, Huai-Chia, Chen, Yi-Ming, Hung, Wei-Ting, Li, Ju-Pi, Chen, Der-Yuan, Lan, Joung-Liang, Tan, Tse-Hua
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2016
Materias:	Research Paper: Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5295375/ https://www.ncbi.nlm.nih.gov/pubmed/27557500 http://dx.doi.org/10.18632/oncotarget.11419

Ejemplares similares

MAP4K Family Kinases and DUSP Family Phosphatases in T-Cell Signaling and Systemic Lupus Erythematosus
por: Chuang, Huai-Chia, et al.
Publicado: (2019)

Regulation of Dual-Specificity Phosphatase (DUSP) Ubiquitination and Protein Stability
por: Chen, Hsueh-Fen, et al.
Publicado: (2019)

Structural Insights into the Active Site Formation of DUSP22 in N-loop-containing Protein Tyrosine Phosphatases
por: Lai, Chih-Hsuan, et al.
Publicado: (2020)

DUSP2 inhibits the progression of lupus nephritis in mice by regulating the STAT3 pathway
por: Liu, Xingzhong, et al.
Publicado: (2023)

Genomic sequencing and functional analyses identify MAP4K3/GLK germline and somatic variants associated with systemic lupus erythematosus
por: Chuang, Huai-Chia, et al.
Publicado: (2022)

Downregulation of JKAP is correlated with elevated disease risk, advanced disease severity, higher inflammation, and poor survival in sepsis
por: Zhao, Min, et al.
Publicado: (2019)

Clinical value of serum JKAP in acute ischemic stroke patients
por: Zhang, Jianli, et al.
Publicado: (2022)

Dual-specificity phosphatases 22-deficient T cells contribute to the pathogenesis of ankylosing spondylitis
por: Chen, Ming-Han, et al.
Publicado: (2023)

Terbinafine Induced Lupus Erythematosus With Progression to Lupus Nephritis
por: Hindosh, Naif, et al.
Publicado: (2022)

Belimumab for systemic lupus erythematosus – Focus on lupus nephritis
por: Plüß, Marlene, et al.
Publicado: (2022)

Hepatocyte phosphatase DUSP22 mitigates NASH-HCC progression by targeting FAK
por: Ge, Chenxu, et al.
Publicado: (2022)

Induction of DUSP14 ubiquitination by PRMT5-mediated arginine methylation
por: Yang, Chia-Yu, et al.
Publicado: (2018)

Systemic lupus erythematosus presenting as lupus erythematosus tumidus and lupus nephritis: a case report
por: Hajji, Meriam, et al.
Publicado: (2023)

Absolute quantification and characterization of oxylipins in lupus nephritis and systemic lupus erythematosus
por: He, Jingquan, et al.
Publicado: (2022)

Systemic lupus erythematosus-myositis overlap syndrome with lupus nephritis
por: Dey, Biswajit, et al.
Publicado: (2020)

DUSP6 Deficiency Attenuates Neurodegeneration after Global Cerebral Ischemia
por: Weng, Yi-Chinn, et al.
Publicado: (2023)

Dickkopf-1 Is a Biomarker for Systemic Lupus Erythematosus and Active Lupus Nephritis
por: Xue, Jing, et al.
Publicado: (2017)

Kikuchi disease preceding systemic lupus erythematosus with membranous lupus nephritis
por: Ponnusamy, Arvind, et al.
Publicado: (2009)

Systemic Lupus Erythematosus in the Elderly That Debuts With an Organic Manifestation of Lupus Nephritis
por: Khan, Anosh, et al.
Publicado: (2022)

Unmasking Renal Disease in Systemic Lupus Erythematosus: Beyond Lupus Nephritis
por: Nunez Cuello, Lisandra, et al.
Publicado: (2023)

JKAP relates to disease risk, severity, and Th1 and Th17 differentiation in Parkinson's disease
por: Yang, Qingwei, et al.
Publicado: (2021)

Endoplasmic Reticulum Stress in Systemic Lupus Erythematosus and Lupus Nephritis: Potential Therapeutic Target
por: Li, Hui-Yuan, et al.
Publicado: (2023)

IMMUNOLOGICAL STUDIES CONCERNING THE NEPHRITIS OF SYSTEMIC LUPUS ERYTHEMATOSUS
por: Koffler, David, et al.
Publicado: (1967)

Systemic lupus erythematosus nephritis and COVID-19 disease
por: Gayathri, C., et al.
Publicado: (2023)

DUSP4 phosphatase puts the brakes on DLBCL
por: Rickert, Robert
Publicado: (2015)

Leukocyte Mitochondrial DNA Alteration in Systemic Lupus Erythematosus and Its Relevance to the Susceptibility to Lupus Nephritis
por: Lee, Hui-Ting, et al.
Publicado: (2012)

BPI overexpression suppresses Treg differentiation and induces exosome-mediated inflammation in systemic lupus erythematosus
por: Chuang, Huai-Chia, et al.
Publicado: (2021)

Alpha-actinin-binding antibodies in relation to systemic lupus erythematosus and lupus nephritis
por: Becker-Merok, Andrea, et al.
Publicado: (2006)

Non-invasive imaging to monitor lupus nephritis and neuropsychiatric systemic lupus erythematosus
por: Thurman, Joshua M., et al.
Publicado: (2015)

Satisfaction with control of systemic lupus erythematosus and lupus nephritis: physician and patient perspectives
por: Mozaffarian, Neelufar, et al.
Publicado: (2016)

Plasma C4d as marker for lupus nephritis in systemic lupus erythematosus
por: Martin, Myriam, et al.
Publicado: (2017)

Disseminated Herpes Zoster on a Child with Systemic Lupus Erythematosus and Lupus Nephritis
por: Widasmara, Dhelya, et al.
Publicado: (2021)

Molecular alterations and tumor suppressive function of the DUSP22 (Dual Specificity Phosphatase 22) gene in peripheral T-cell lymphoma subtypes
por: Mélard, Pierre, et al.
Publicado: (2016)

Altered expression of protein tyrosine phosphatase, non-receptor type 22 isoforms in systemic lupus erythematosus
por: Chang, Hui-Hsin, et al.
Publicado: (2014)

SYSTEMIC LUPUS ERYTHEMATOSUS: PROTOTYPE OF IMMUNE COMPLEX NEPHRITIS IN MAN
por: Koffler, D., et al.
Publicado: (1971)

Performance of the 2019 EULAR/ACR systemic lupus erythematosus classification criteria in a cohort of patients with biopsy-confirmed lupus nephritis
por: Wang, Huijing, et al.
Publicado: (2021)

Occult systemic lupus erythematosus with active lupus nephritis presenting as Libman-Sacks endocarditis
por: Kasar, Pankajkumar Ashok, et al.
Publicado: (2012)

Dengue fever triggering systemic lupus erythematosus and lupus nephritis: a case report
por: Talib, SH, et al.
Publicado: (2013)

Calcineurin and Systemic Lupus Erythematosus: The Rationale for Using Calcineurin Inhibitors in the Treatment of Lupus Nephritis
por: Rafael-Vidal, Carlos, et al.
Publicado: (2021)

Mobile health apps for systemic lupus erythematosus and lupus nephritis: a critical appraisal
por: Ramasamy, Akshara, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_155vv9g0lfe8k95jfp9ev1lh6n