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A cancer specific hypermethylation signature of the TERT promoter predicts biochemical relapse in prostate cancer: a retrospective cohort study

The identification of new biomarkers to differentiate between indolent and aggressive prostate tumors is an important unmet need. We examined the role of THOR (TERT Hypermethylated Oncological Region) as a diagnostic and prognostic biomarker in prostate cancer (PCa). We analyzed THOR in common cance...

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Detalles Bibliográficos
Autores principales: Castelo-Branco, Pedro, Leão, Ricardo, Lipman, Tatiana, Campbell, Brittany, Lee, Donghyun, Price, Aryeh, Zhang, Cindy, Heidari, Abolfazl, Stephens, Derek, Boerno, Stefan, Coelho, Hugo, Gomes, Ana, Domingos, Celia, Apolonio, Joana D., Schäfer, Georg, Bristow, Robert G., Schweiger, Michal R., Hamilton, Robert, Zlotta, Alexandre, Figueiredo, Arnaldo, Klocker, Helmut, Sültmann, Holger, Tabori, Uri
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5295385/
https://www.ncbi.nlm.nih.gov/pubmed/27437772
http://dx.doi.org/10.18632/oncotarget.10639