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CD147 knockdown improves the antitumor efficacy of trastuzumab in HER2-positive breast cancer cells

Trastuzumab is widely used in the clinical treatment of human epidermal growth factor receptor-2 (HER2)-positive breast cancer, but the patient response rate is low. CD147 stimulates cancer cell proliferation, migration, metastasis and differentiation and is involved in chemoresistance in many types...

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Detalles Bibliográficos
Autores principales: Xiong, Lijuan, Ding, Li, Ning, Haoyong, Wu, Chenglin, Fu, Kaifei, Wang, Yuxiao, Zhang, Yan, Liu, Yan, Zhou, Lijun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5295386/
https://www.ncbi.nlm.nih.gov/pubmed/27363028
http://dx.doi.org/10.18632/oncotarget.10252