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Her2 oncogene transformation enhances 5-aminolevulinic acid-mediated protoporphyrin IX production and photodynamic therapy response

Enhanced protoporphyrin IX (PpIX) production in tumors derived from the administration of 5-aminolevulinic acid (ALA) enables the use of ALA as a prodrug for photodynamic therapy (PDT) and fluorescence-guided tumor resection. Although ALA has been successfully used in the clinic, the mechanism under...

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Detalles Bibliográficos
Autores principales: Yang, Xue, Palasuberniam, Pratheeba, Myers, Kenneth A., Wang, Chenguang, Chen, Bin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5295390/
https://www.ncbi.nlm.nih.gov/pubmed/27527860
http://dx.doi.org/10.18632/oncotarget.11058