Acute myeloid leukemia stem cell markers in prognosis and targeted therapy: potential impact of BMI-1, TIM-3 and CLL-1

Acute myeloid leukemia (AML) patients show high relapse rates and some develop conventional chemotherapy resistance. Leukemia Stem Cells (LSCs) are the main player for AML relapses and drug resistance. LSCs might rely on the B-cell-specific Moloney murine leukemia virus integration site-1 (BMI-1) in...

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Detalles Bibliográficos
Autores principales: Darwish, Noureldien H.E., Sudha, Thangirala, Godugu, Kavitha, Elbaz, Osama, Abdelghaffar, Hasan A., Hassan, Emad E.A., Mousa, Shaker A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5295391/
https://www.ncbi.nlm.nih.gov/pubmed/27506934
http://dx.doi.org/10.18632/oncotarget.11063

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5295391/
https://www.ncbi.nlm.nih.gov/pubmed/27506934
http://dx.doi.org/10.18632/oncotarget.11063

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