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Inhibition of PlexA1-mediated brain tumor growth and tumor-associated angiogenesis using a transmembrane domain targeting peptide

The neuropilin-plexin receptor complex regulates tumor cell migration and proliferation and thus is an interesting therapeutic target. High expression of neuropilin-1 is indeed associated with a bad prognosis in glioma patients. Q-RTPCR and tissue-array analyses showed here that Plexin-A1 is highly...

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Detalles Bibliográficos
Autores principales: Jacob, Laurent, Sawma, Paul, Garnier, Norbert, Meyer, Lionel A.T., Fritz, Justine, Hussenet, Thomas, Spenlé, Caroline, Goetz, Jacky, Vermot, Julien, Fernandez, Aurore, Baumlin, Nadège, Aci-Sèche, Samia, Orend, Gertraud, Roussel, Guy, Crémel, Gérard, Genest, Monique, Hubert, Pierre, Bagnard, Dominique
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5295395/
https://www.ncbi.nlm.nih.gov/pubmed/27506939
http://dx.doi.org/10.18632/oncotarget.11072