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RSUME is implicated in tumorigenesis and metastasis of pancreatic neuroendocrine tumors

The factors triggering pancreatic neuroendocrine tumor (PanNET) progression are largely unknown. Here we investigated the role and mechanisms of the sumoylation enhancing protein RSUME in PanNET tumorigenesis. Immunohistochemical studies showed that RSUME is strongly expressed in normal human pancre...

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Detalles Bibliográficos
Autores principales: Wu, Yonghe, Tedesco, Lucas, Lucia, Kristin, Schlitter, Anna M., Garcia, Jose Monteserin, Esposito, Irene, Auernhammer, Christoph J., Theodoropoulou, Marily, Arzt, Eduardo, Renner, Ulrich, Stalla, Günter K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5295397/
https://www.ncbi.nlm.nih.gov/pubmed/27506944
http://dx.doi.org/10.18632/oncotarget.11081