Aberrant DR5 transport through disruption of lysosomal function suggests a novel mechanism for receptor activation

To examine reciprocal or unilateral implications between two cell destruction processes, autophagy and apoptosis, in 5-Fluorouracil (5-FU)-treated tumor cells, a combination of chemical inhibitors, RNAi and genetic approaches were used. In contrast to cancer cells harboring obstructed apoptosis, eit...

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Detalles Bibliográficos
Autores principales: Akpinar, Birce, Safarikova, Barbora, Laukova, Jarmila, Debnath, Shubhranshu, Vaculova, Alena Hyrslova, Zhivotovsky, Boris, Olsson, Magnus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5295431/
https://www.ncbi.nlm.nih.gov/pubmed/27506940
http://dx.doi.org/10.18632/oncotarget.11073

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5295431/
https://www.ncbi.nlm.nih.gov/pubmed/27506940
http://dx.doi.org/10.18632/oncotarget.11073

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