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CD44 and CD24 coordinate the reprogramming of nasopharyngeal carcinoma cells towards a cancer stem cell phenotype through STAT3 activation

Cell surface proteins such as CD44 and CD24 are used to distinguish cancer stem cells (CSCs) from the bulk-tumor population. However, the molecular functionalities of CD24 and CD44, and how these two molecules coordinate in CSCs remain poorly understood. We found that nasopharyngeal carcinoma (NPC)...

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Detalles Bibliográficos
Autores principales: Shen, Yao-An, Wang, Chia-Yu, Chuang, Hui-Yen, Hwang, John Jeng-Jong, Chi, Wei-Hsin, Shu, Chih-Hung, Ho, Ching-Yin, Li, Wing-Yin, Chen, Yann-Jang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5295435/
https://www.ncbi.nlm.nih.gov/pubmed/27521216
http://dx.doi.org/10.18632/oncotarget.11113