Cargando…
CD44 and CD24 coordinate the reprogramming of nasopharyngeal carcinoma cells towards a cancer stem cell phenotype through STAT3 activation
Cell surface proteins such as CD44 and CD24 are used to distinguish cancer stem cells (CSCs) from the bulk-tumor population. However, the molecular functionalities of CD24 and CD44, and how these two molecules coordinate in CSCs remain poorly understood. We found that nasopharyngeal carcinoma (NPC)...
Autores principales: | Shen, Yao-An, Wang, Chia-Yu, Chuang, Hui-Yen, Hwang, John Jeng-Jong, Chi, Wei-Hsin, Shu, Chih-Hung, Ho, Ching-Yin, Li, Wing-Yin, Chen, Yann-Jang |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5295435/ https://www.ncbi.nlm.nih.gov/pubmed/27521216 http://dx.doi.org/10.18632/oncotarget.11113 |
Ejemplares similares
-
STAT3 mediates resistance of CD44(+)CD24(−/low) breast cancer stem cells to tamoxifen in vitro
por: Wang, Xiaoyan, et al.
Publicado: (2012) -
Evaluation of STAT3 Signaling in ALDH+ and ALDH+/CD44+/CD24− Subpopulations of Breast Cancer Cells
por: Lin, Li, et al.
Publicado: (2013) -
Downregulation of CD44 reduces doxorubicin resistance of CD44(+)CD24(−) breast cancer cells
por: Van Phuc, Pham, et al.
Publicado: (2011) -
FLJ10540 is associated with tumor progression in nasopharyngeal carcinomas and contributes to nasopharyngeal cell proliferation, and metastasis via osteopontin/CD44 pathway
por: Chen, Chang-Han, et al.
Publicado: (2012) -
STAT3 as a potential therapeutic target in ALDH(+) and CD44(+)/CD24(+) stem cell-like pancreatic cancer cells
por: Lin, Li, et al.
Publicado: (2016)