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Doxorubicin-triggered self-assembly of native amphiphilic peptides into spherical nanoparticles

In this study, we designed and fabricated self-assembly nanospheres, which consisted of a P45 peptide and doxorubicin (Dox). P45 is a hybrid peptide composed of an Arg-Gly-Asp motif linked to the human matrilin-1 C-terminal domain by a serine linker. The fabricated nanospheres had a uniform mulberry...

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Detalles Bibliográficos
Autores principales: Fan, Xiaobo, Zhao, Fengfeng, Wang, Xiyong, Wu, Guoqiu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5295442/
https://www.ncbi.nlm.nih.gov/pubmed/27533248
http://dx.doi.org/10.18632/oncotarget.11213