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Doxorubicin-triggered self-assembly of native amphiphilic peptides into spherical nanoparticles
In this study, we designed and fabricated self-assembly nanospheres, which consisted of a P45 peptide and doxorubicin (Dox). P45 is a hybrid peptide composed of an Arg-Gly-Asp motif linked to the human matrilin-1 C-terminal domain by a serine linker. The fabricated nanospheres had a uniform mulberry...
Autores principales: | Fan, Xiaobo, Zhao, Fengfeng, Wang, Xiyong, Wu, Guoqiu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5295442/ https://www.ncbi.nlm.nih.gov/pubmed/27533248 http://dx.doi.org/10.18632/oncotarget.11213 |
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