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Targeting a novel cancer-driving protein (LAPTM4B-35) by a small molecule (ETS) to inhibit cancer growth and metastasis

Our previous studies demonstrated that LAPTM4B-35 is overexpressed in a variety of solid cancers including hepatocellular carcinoma (HCC), and is an independent factor for prognosis. LAPTM4B-35 overexpression causes carcinogenesis and enhances cancer growth, metastasis and multidrug resistance, and...

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Detalles Bibliográficos
Autores principales: Li, Maojin, Zhou, Rouli, Shan, Yi, Li, Li, Wang, Lin, Liu, Gang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5295449/
https://www.ncbi.nlm.nih.gov/pubmed/27542271
http://dx.doi.org/10.18632/oncotarget.11325