Haemolysis in G6PD Heterozygous Females Treated with Primaquine for Plasmodium vivax Malaria: A Nested Cohort in a Trial of Radical Curative Regimens

BACKGROUND: Radical cure of Plasmodium vivax malaria with 8-aminoquinolines (primaquine or tafenoquine) is complicated by haemolysis in individuals with glucose-6-phosphate dehydrogenase (G6PD) deficiency. G6PD heterozygous females, because of individual variation in the pattern of X-chromosome inac...

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Detalles Bibliográficos
Autores principales: Chu, Cindy S., Bancone, Germana, Moore, Kerryn A., Win, Htun Htun, Thitipanawan, Niramon, Po, Christina, Chowwiwat, Nongnud, Raksapraidee, Rattanaporn, Wilairisak, Pornpimon, Phyo, Aung Pyae, Keereecharoen, Lily, Proux, Stéphane, Charunwatthana, Prakaykaew, Nosten, François, White, Nicholas J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5295665/
https://www.ncbi.nlm.nih.gov/pubmed/28170391
http://dx.doi.org/10.1371/journal.pmed.1002224

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5295665/
https://www.ncbi.nlm.nih.gov/pubmed/28170391
http://dx.doi.org/10.1371/journal.pmed.1002224

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