Cholesterol contributes to dopamine-neuronal loss in MPTP mouse model of Parkinson’s disease: Involvement of mitochondrial dysfunctions and oxidative stress

Hypercholesterolemia is a known contributor to the pathogenesis of Alzheimer’s disease while its role in the occurrence of Parkinson’s disease (PD) is only conjecture and far from conclusive. Altered antioxidant homeostasis and mitochondrial functions are the key mechanisms in loss of dopaminergic n...

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Detalles Bibliográficos
Autores principales: Paul, Rajib, Choudhury, Amarendranath, Kumar, Sanjeev, Giri, Anirudha, Sandhir, Rajat, Borah, Anupom
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5295696/
https://www.ncbi.nlm.nih.gov/pubmed/28170429
http://dx.doi.org/10.1371/journal.pone.0171285

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5295696/
https://www.ncbi.nlm.nih.gov/pubmed/28170429
http://dx.doi.org/10.1371/journal.pone.0171285

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