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Cholesterol contributes to dopamine-neuronal loss in MPTP mouse model of Parkinson’s disease: Involvement of mitochondrial dysfunctions and oxidative stress
Hypercholesterolemia is a known contributor to the pathogenesis of Alzheimer’s disease while its role in the occurrence of Parkinson’s disease (PD) is only conjecture and far from conclusive. Altered antioxidant homeostasis and mitochondrial functions are the key mechanisms in loss of dopaminergic n...
Autores principales: | Paul, Rajib, Choudhury, Amarendranath, Kumar, Sanjeev, Giri, Anirudha, Sandhir, Rajat, Borah, Anupom |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5295696/ https://www.ncbi.nlm.nih.gov/pubmed/28170429 http://dx.doi.org/10.1371/journal.pone.0171285 |
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