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The effect of dietary fish oil on weight gain and insulin sensitivity is dependent on APOE genotype in humanized targeted replacement mice

We investigated the independent and interactive impact of the common APOE genotype and marine n-3 polyunsaturated fatty acids (PUFAs) on the development of obesity and associated cardiometabolic dysfunction in a murine model. Human APOE3 and APOE4 targeted replacement mice were fed either a control...

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Detalles Bibliográficos
Autores principales: Slim, Kenna E., Vauzour, David, Tejera, Noemi, Voshol, Peter J., Cassidy, Aedin, Minihane, Anne Marie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Federation of American Societies for Experimental Biology 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5295733/
https://www.ncbi.nlm.nih.gov/pubmed/27895108
http://dx.doi.org/10.1096/fj.201600921RR