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AR-Signaling in Human Malignancies: Prostate Cancer and Beyond

In the 1940s Charles Huggins reported remarkable palliative benefits following surgical castration in men with advanced prostate cancer, and since then the androgen receptor (AR) has remained the main therapeutic target in this disease. Over the past couple of decades, our understanding of AR-signal...

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Detalles Bibliográficos
Autores principales: Schweizer, Michael T., Yu, Evan Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5295778/
https://www.ncbi.nlm.nih.gov/pubmed/28085048
http://dx.doi.org/10.3390/cancers9010007