Screening and Characterization of Drugs That Protect Corneal Endothelial Cells Against Unfolded Protein Response and Oxidative Stress

PURPOSE: To screen for and characterize compounds that protect corneal endothelial cells against unfolded protein response (UPR) and oxidative stress. METHODS: Bovine corneal endothelial cells (BCECs) were treated for 48 hours with 640 compounds from a Food and Drug Administration (FDA)-approved dru...

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Detalles Bibliográficos
Autores principales: Kim, Eun Chul, Toyono, Tetsuya, Berlinicke, Cynthia A., Zack, Donald J., Jurkunas, Ula, Usui, Tomohiko, Jun, Albert S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2017
Materias:
Cornea
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5295784/
https://www.ncbi.nlm.nih.gov/pubmed/28159976
http://dx.doi.org/10.1167/iovs.16-20147

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5295784/
https://www.ncbi.nlm.nih.gov/pubmed/28159976
http://dx.doi.org/10.1167/iovs.16-20147

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