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ERG-28 controls BK channel trafficking in the ER to regulate synaptic function and alcohol response in C. elegans

Voltage- and calcium-dependent BK channels regulate calcium-dependent cellular events such as neurotransmitter release by limiting calcium influx. Their plasma membrane abundance is an important factor in determining BK current and thus regulation of calcium-dependent events. In C. elegans, we show...

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Detalles Bibliográficos
Autores principales: Oh, Kelly H, Haney, James J, Wang, Xiaohong, Chuang, Chiou-Fen, Richmond, Janet E, Kim, Hongkyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5295816/
https://www.ncbi.nlm.nih.gov/pubmed/28168949
http://dx.doi.org/10.7554/eLife.24733