Dendritic cells engineered to secrete anti-DcR3 antibody augment cytotoxic T lymphocyte response against pancreatic cancer in vitro

AIM: To investigate the enhanced cytotoxic T lymphocyte responses against pancreatic cancer (PC) in vitro induced by dendritic cells (DCs) engineered to secrete anti-DcR3 monoclonal antibody (mAb). METHODS: DCs, T lymphocytes and primary PC cells were obtained from PC patients. DCs were transfected...

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Detalles Bibliográficos
Autores principales: Chen, Jiang, Guo, Xiao-Zhong, Li, Hong-Yu, Zhao, Jia-Jun, Xu, Wen-Da
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Baishideng Publishing Group Inc 2017
Materias:
Basic Study
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5296198/
https://www.ncbi.nlm.nih.gov/pubmed/28223726
http://dx.doi.org/10.3748/wjg.v23.i5.817

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5296198/
https://www.ncbi.nlm.nih.gov/pubmed/28223726
http://dx.doi.org/10.3748/wjg.v23.i5.817

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