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PP2A(Cdc55) Phosphatase Imposes Ordered Cell-Cycle Phosphorylation by Opposing Threonine Phosphorylation

In the quantitative model of cell-cycle control, progression from G1 through S phase and into mitosis is ordered by thresholds of increasing cyclin-dependent kinase (Cdk) activity. How such thresholds are read out by substrates that respond with the correct phosphorylation timing is not known. Here,...

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Detalles Bibliográficos
Autores principales: Godfrey, Molly, Touati, Sandra A., Kataria, Meghna, Jones, Andrew, Snijders, Ambrosius P., Uhlmann, Frank
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5296252/
https://www.ncbi.nlm.nih.gov/pubmed/28132839
http://dx.doi.org/10.1016/j.molcel.2016.12.018