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Intranasal BMP9 Ameliorates Alzheimer Disease-Like Pathology and Cognitive Deficits in APP/PS1 Transgenic Mice

Alzheimer’s disease (AD) is the most common type of dementia and has no effective therapies. Previous studies showed that bone morphogenetic protein 9 (BMP9), an important factor in the differentiation and phenotype maintenance of cholinergic neurons, ameliorated the cholinergic defects resulting fr...

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Detalles Bibliográficos
Autores principales: Wang, Zigao, Xiong, Lu, Wan, Wenbin, Duan, Lijie, Bai, Xiaojing, Zu, Hengbing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5296319/
https://www.ncbi.nlm.nih.gov/pubmed/28228716
http://dx.doi.org/10.3389/fnmol.2017.00032