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Intranasal BMP9 Ameliorates Alzheimer Disease-Like Pathology and Cognitive Deficits in APP/PS1 Transgenic Mice
Alzheimer’s disease (AD) is the most common type of dementia and has no effective therapies. Previous studies showed that bone morphogenetic protein 9 (BMP9), an important factor in the differentiation and phenotype maintenance of cholinergic neurons, ameliorated the cholinergic defects resulting fr...
Autores principales: | Wang, Zigao, Xiong, Lu, Wan, Wenbin, Duan, Lijie, Bai, Xiaojing, Zu, Hengbing |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5296319/ https://www.ncbi.nlm.nih.gov/pubmed/28228716 http://dx.doi.org/10.3389/fnmol.2017.00032 |
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