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Proofreading of Peptide—MHC Complexes through Dynamic Multivalent Interactions

The adaptive immune system is able to detect and destroy cells that are malignantly transformed or infected by intracellular pathogens. Specific immune responses against these cells are elicited by antigenic peptides that are presented on major histocompatibility complex class I (MHC I) molecules an...

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Detalles Bibliográficos
Autores principales: Thomas, Christoph, Tampé, Robert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5296336/
https://www.ncbi.nlm.nih.gov/pubmed/28228754
http://dx.doi.org/10.3389/fimmu.2017.00065