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Metabolic and Cardiovascular Benefits and Risks of EMD386088—A 5-HT(6) Receptor Partial Agonist and Dopamine Transporter Inhibitor
Since 5-HT(6) receptors play role in controlling feeding and satiety and dopamine is essential for normal feeding behavior, we evaluated the ability of EMD 386088—5-HT(6) receptor partial agonist and dopamine transporter inhibitor—to reduce body weight in obese rats, as well as its anorectic propert...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5296348/ https://www.ncbi.nlm.nih.gov/pubmed/28228713 http://dx.doi.org/10.3389/fnins.2017.00050 |