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β Subunits Functionally Differentiate Human Kv4.3 Potassium Channel Splice Variants
The human ventricular cardiomyocyte transient outward K(+) current (I(to)) mediates the initial phase of myocyte repolarization and its disruption is implicated in Brugada Syndrome and heart failure (HF). Human cardiac I(to) is generated primarily by two Kv4.3 splice variants (Kv4.3L and Kv4.3S, div...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Frontiers Media S.A.
2017
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5296356/ https://www.ncbi.nlm.nih.gov/pubmed/28228734 http://dx.doi.org/10.3389/fphys.2017.00066 |