Cargando…

β Subunits Functionally Differentiate Human Kv4.3 Potassium Channel Splice Variants

The human ventricular cardiomyocyte transient outward K(+) current (I(to)) mediates the initial phase of myocyte repolarization and its disruption is implicated in Brugada Syndrome and heart failure (HF). Human cardiac I(to) is generated primarily by two Kv4.3 splice variants (Kv4.3L and Kv4.3S, div...

Descripción completa

Detalles Bibliográficos
Autor principal:	Abbott, Geoffrey W.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2017
Materias:	Physiology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5296356/ https://www.ncbi.nlm.nih.gov/pubmed/28228734 http://dx.doi.org/10.3389/fphys.2017.00066

Ejemplares similares

β Subunits Control the Effects of Human Kv4.3 Potassium Channel Phosphorylation
por: Abbott, Geoffrey W.
Publicado: (2017)

The Gβ1 and Gβ3 Subunits Differentially Regulate Rat Vascular Kv7 Channels
por: Greenwood, Iain A., et al.
Publicado: (2020)

Oligomerization and Spatial Distribution of Kvβ1.1 and Kvβ2.1 Regulatory Subunits
por: Roig, Sara R., et al.
Publicado: (2022)

KCNQs: Ligand- and Voltage-Gated Potassium Channels
por: Abbott, Geoffrey W.
Publicado: (2020)

Cyclic AMP-Dependent Regulation of Kv7 Voltage-Gated Potassium Channels
por: van der Horst, Jennifer, et al.
Publicado: (2020)

Heteromeric Channels Formed From Alternating Kv7.4 and Kv7.5 α-Subunits Display Biophysical, Regulatory, and Pharmacological Characteristics of Smooth Muscle M-Currents
por: Brueggemann, Lyubov I., et al.
Publicado: (2020)

Kv7/M-type potassium channels in rat skin keratinocytes
por: Reilly, Joanne M., et al.
Publicado: (2013)

Palmitoylation of the β4-Subunit Regulates Surface Expression of Large Conductance Calcium-activated Potassium Channel Splice Variants
por: Chen, Lie, et al.
Publicado: (2013)

Kv7 Channels in Lung Diseases
por: Mondejar-Parreño, Gema, et al.
Publicado: (2020)

Functional specification of CCK+ interneurons by alternative isoforms of Kv4.3 auxiliary subunits
por: Oláh, Viktor János, et al.
Publicado: (2020)

Jingzhaotoxin-X, a gating modifier of Kv4.2 and Kv4.3 potassium channels purified from the venom of the Chinese tarantula Chilobrachys jingzhao
por: Deng, Meichun, et al.
Publicado: (2020)

Impact of KvLQT1 potassium channel modulation on alveolar fluid homeostasis in an animal model of thiourea-induced lung edema
por: Aubin Vega, Mélissa, et al.
Publicado: (2023)

Delayed Rectifier and A-Type Potassium Channels Associated with Kv 2.1 and Kv 4.3 Expression in Embryonic Rat Neural Progenitor Cells
por: Smith, Dean O., et al.
Publicado: (2008)

The S2–S3 Loop of Kv7.4 Channels Is Essential for Calmodulin Regulation of Channel Activation
por: Zhuang, Wenhui, et al.
Publicado: (2021)

The Functional Availability of Arterial Kv7 Channels Is Suppressed Considerably by Large-Conductance Calcium-Activated Potassium Channels in 2- to 3-Month Old but Not in 10- to 15-Day Old Rats
por: Ma, Dongyu, et al.
Publicado: (2020)

Mechanism of functional interaction between potassium channel Kv1.3 and sodium channel NavBeta1 subunit
por: Kubota, Tomoya, et al.
Publicado: (2017)

The focal adhesion protein Testin modulates KCNE2 potassium channel β subunit activity
por: Papanikolaou, Maria, et al.
Publicado: (2021)

The voltage-dependent K(+) channels Kv1.3 and Kv1.5 in human cancer
por: Comes, Núria, et al.
Publicado: (2013)

Open channel block of Kv1.4 potassium channels by aripiprazole
por: Park, Jeaneun, et al.
Publicado: (2020)

Expression, Cellular and Subcellular Localisation of Kv4.2 and Kv4.3 Channels in the Rodent Hippocampus
por: Alfaro-Ruíz, Rocío, et al.
Publicado: (2019)

Site-specific contacts enable distinct modes of TRPV1 regulation by the potassium channel Kvβ1 subunit
por: Wang, Yuanyuan, et al.
Publicado: (2020)

Auxiliary subunits control biophysical properties and response to compound NS5806 of the Kv4 potassium channel complex
por: Zhang, Hongxue, et al.
Publicado: (2019)

Proliferative Role of Kv11 Channels in Murine Arteries
por: Barrese, Vincenzo, et al.
Publicado: (2017)

Editorial: Kv7 Channels: Structure, Physiology, and Pharmacology
por: Jepps, Thomas A., et al.
Publicado: (2021)

Kv1.1 potassium channel subunit deficiency alters ventricular arrhythmia susceptibility, contractility, and repolarization
por: Trosclair, Krystle, et al.
Publicado: (2021)

Kv1.1 channel subunits in the control of neurocardiac function
por: Glasscock, Edward
Publicado: (2019)

Regulation of Kv1.4 potassium channels by PKC and AMPK kinases
por: Andersen, Martin Nybo, et al.
Publicado: (2017)

A Novel Kv7.3 Variant in the Voltage-Sensing S(4) Segment in a Family With Benign Neonatal Epilepsy: Functional Characterization and in vitro Rescue by β-Hydroxybutyrate
por: Miceli, Francesco, et al.
Publicado: (2020)

Cdk-mediated phosphorylation of the Kvβ2 auxiliary subunit regulates Kv1 channel axonal targeting
por: Vacher, Hélène, et al.
Publicado: (2011)

Pharmacological consequences of the coexpression of BK channel α and auxiliary β subunits
por: Torres, Yolima P., et al.
Publicado: (2014)

Location of modulatory β subunits in BK potassium channels
por: Liu, Guoxia, et al.
Publicado: (2010)

Fluorescence Fluctuation Spectroscopy enables quantification of potassium channel subunit dynamics and stoichiometry
por: Tedeschi, Giulia, et al.
Publicado: (2021)

Kvβ1.2 Subunit Coexpression in HEK293 Cells Confers O(2 )Sensitivity to Kv4.2 but not to Shaker Channels
por: Pérez-García, María Teresa, et al.
Publicado: (1999)

Auxiliary KCNE subunits modulate both homotetrameric Kv2.1 and heterotetrameric Kv2.1/Kv6.4 channels
por: David, Jens-Peter, et al.
Publicado: (2015)

Potassium-dependent Changes in the Conformation of the Kv2.1 Potassium Channel Pore
por: Immke, David, et al.
Publicado: (1999)

Kv4.2 potassium channels segregate to extrasynaptic domains and influence intrasynaptic NMDA receptor NR2B subunit expression
por: Kaufmann, Walter A., et al.
Publicado: (2012)

The Electrically Silent Kv6.4 Subunit Confers Hyperpolarized Gating Charge Movement in Kv2.1/Kv6.4 Heterotetrameric Channels
por: Bocksteins, Elke, et al.
Publicado: (2012)

Regulation of Kv4.3 and hERG potassium channels by KChIP2 isoforms and DPP6 and response to the dual K(+) channel activator NS3623
por: Lainez, Sergio, et al.
Publicado: (2018)

Calmodulin: A Multitasking Protein in Kv7.2 Potassium Channel Functions
por: Alaimo, Alessandro, et al.
Publicado: (2018)

Mitochondrial Ultrastructure and Glucose Signaling Pathways Attributed to the Kv1.3 Ion Channel
por: Kovach, Christopher P., et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_6ua05ce4p55i3v07g6qnth52cq