Cargando…

Pif1-family helicases cooperate to suppress widespread replication fork arrest at tRNA genes

Saccharomyces cerevisiae encodes two distinct Pif1-family helicases – Pif1 and Rrm3 – which have been reported to play distinct roles in numerous nuclear processes. Here, we systematically characterize the roles of Pif1 helicases in replisome progression and lagging-strand synthesis in S. cerevisiae...

Descripción completa

Detalles Bibliográficos
Autores principales: Osmundson, Joseph S., Kumar, Jayashree, Yeung, Rani, Smith, Duncan J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5296403/
https://www.ncbi.nlm.nih.gov/pubmed/27991904
http://dx.doi.org/10.1038/nsmb.3342