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Pif1-family helicases cooperate to suppress widespread replication fork arrest at tRNA genes
Saccharomyces cerevisiae encodes two distinct Pif1-family helicases – Pif1 and Rrm3 – which have been reported to play distinct roles in numerous nuclear processes. Here, we systematically characterize the roles of Pif1 helicases in replisome progression and lagging-strand synthesis in S. cerevisiae...
Autores principales: | Osmundson, Joseph S., Kumar, Jayashree, Yeung, Rani, Smith, Duncan J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5296403/ https://www.ncbi.nlm.nih.gov/pubmed/27991904 http://dx.doi.org/10.1038/nsmb.3342 |
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