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Selective Whole-Genome Amplification Is a Robust Method That Enables Scalable Whole-Genome Sequencing of Plasmodium vivax from Unprocessed Clinical Samples

Whole-genome sequencing (WGS) of microbial pathogens from clinical samples is a highly sensitive tool used to gain a deeper understanding of the biology, epidemiology, and drug resistance mechanisms of many infections. However, WGS of organisms which exhibit low densities in their hosts is challengi...

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Detalles Bibliográficos
Autores principales: Cowell, Annie N., Loy, Dorothy E., Sundararaman, Sesh A., Valdivia, Hugo, Fisch, Kathleen, Lescano, Andres G., Baldeviano, G. Christian, Durand, Salomon, Gerbasi, Vince, Sutherland, Colin J., Nolder, Debbie, Vinetz, Joseph M., Hahn, Beatrice H., Winzeler, Elizabeth A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5296604/
https://www.ncbi.nlm.nih.gov/pubmed/28174312
http://dx.doi.org/10.1128/mBio.02257-16