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ATP-Dependent Persister Formation in Escherichia coli

Persisters are dormant variants that form a subpopulation of cells tolerant to antibiotics. Persisters are largely responsible for the recalcitrance of chronic infections to therapy. In Escherichia coli, one widely accepted model of persister formation holds that stochastic accumulation of ppGpp cau...

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Detalles Bibliográficos
Autores principales: Shan, Yue, Brown Gandt, Autumn, Rowe, Sarah E., Deisinger, Julia P., Conlon, Brian P., Lewis, Kim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5296605/
https://www.ncbi.nlm.nih.gov/pubmed/28174313
http://dx.doi.org/10.1128/mBio.02267-16