Cargando…

Dysfunction of ventrolateral striatal dopamine receptor type 2-expressing medium spiny neurons impairs instrumental motivation

Impaired motivation is present in a variety of neurological disorders, suggesting that decreased motivation is caused by broad dysfunction of the nervous system across a variety of circuits. Based on evidence that impaired motivation is a major symptom in the early stages of Huntington's diseas...

Descripción completa

Detalles Bibliográficos
Autores principales: Tsutsui-Kimura, Iku, Takiue, Hiroyuki, Yoshida, Keitaro, Xu, Ming, Yano, Ryutaro, Ohta, Hiroyuki, Nishida, Hiroshi, Bouchekioua, Youcef, Okano, Hideyuki, Uchigashima, Motokazu, Watanabe, Masahiko, Takata, Norio, Drew, Michael R., Sano, Hiromi, Mimura, Masaru, Tanaka, Kenji F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5296642/
https://www.ncbi.nlm.nih.gov/pubmed/28145402
http://dx.doi.org/10.1038/ncomms14304