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HOPX hypermethylation promotes metastasis via activating SNAIL transcription in nasopharyngeal carcinoma
Nasopharyngeal carcinoma (NPC) is characterized by a high rate of local invasion and early distant metastasis. Increasing evidence indicates that epigenetic abnormalities play important roles in NPC development. However, the epigenetic mechanisms underlying NPC metastasis remain unclear. Here we inv...
Autores principales: | , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5296651/ https://www.ncbi.nlm.nih.gov/pubmed/28146149 http://dx.doi.org/10.1038/ncomms14053 |