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Molecular basis for protection of ribosomal protein L4 from cellular degradation

Eukaryotic ribosome biogenesis requires the nuclear import of ∼80 nascent ribosomal proteins and the elimination of excess amounts by the cellular degradation machinery. Assembly chaperones recognize nascent unassembled ribosomal proteins and transport them together with karyopherins to their nuclea...

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Detalles Bibliográficos
Autores principales: Huber, Ferdinand M., Hoelz, André
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5296656/
https://www.ncbi.nlm.nih.gov/pubmed/28148929
http://dx.doi.org/10.1038/ncomms14354